PROCUREMENT OF VACCINES
Universal Immunization Programme
| Antigen-wise Achievement
|
Vaccines Manufacturing Centres
| Cold Chain equipment
| Drugs |
UNIVERSAL IMMUNISATION PROGRAMME
Universal Immunisation Programme is being conducted in the country for vaccine preventable diseases. Under this programme every year, about 25 million infants are to be vaccinated before they are one year old with three doses of DPT vaccine (Diphtheria, Pertussis and Tetanus), three doses of polio vaccine and one dose each of the measles and BCG vaccines. About 27 million pregnant women were also to be administered two doses of Tetanus Toxoid (TT) as prevention against tetanus to them and their new born.
ANTIGEN-WISE
ACHIEVEMENT
The year-wise and antigen-wise achievement during 1989-90 to 2000-01 is given below:-
|
Year |
DPT |
OPV |
BCG |
Measles |
TT(PW) |
|
(Achievement as Percentage of Annual Targets) |
|||||
|
1989-90 |
82.93 |
82.30 |
89.04 |
69.32 |
58.83 |
|
1990-91 |
100.72 |
101.54 |
102.99 |
90.85 |
79.70 |
|
1991-92 |
90.89 |
91.26 |
92.83 |
84.99 |
77.57 |
|
1992-93 |
90.53 |
91.04 |
96.54 |
85.82 |
79.18 |
|
1993-94 |
93.20 |
93.57 |
97.20 |
88.51 |
82.60 |
|
1994-95 |
94.51 |
95.21 |
99.75 |
87.23 |
83.82 |
|
1995-96 |
90.72 |
91.61 |
97.07 |
82.83 |
80.36 |
|
1996-97 |
91.5 |
92.7 |
98.2 |
83.2 |
81.8 |
|
1997-98 |
92.9 |
93.9 |
99.5 |
85.8 |
82.6 |
|
1998-99 |
93.7 |
95.3 |
97.7 |
88.1 |
83.9 |
|
1999-2000* |
95.3 |
95.9 |
101.6 |
89.8 |
81.3 |
|
2000-01* |
100.3 |
98.2 |
102.7 |
92.1 |
83.4 |
* - Figures provisional
The immunization programme has been a notable success and the infants coverage of the order 85-90% was achieved for the country as a whole by the end of the Eighth Plan. The coverage of infants during 1999-2000 varied from 82-102%. The incidence of related diseases has dramatically come down as indicated in the table below:
|
|
Reported Incidence(1990) |
Reported Incidence(1998) |
Reported Incidence(1999) |
|
Diphtheria |
8425 |
2694 |
2917 |
|
Tetanus |
23356 |
9821 |
4818 |
|
Polio |
10408 |
1949 |
1126 |
|
Measles |
87448 |
38949 |
36575 |
|
Vaccine |
Name of manufacturing unit |
Annual Capacity (In million doses) |
|
Tetanus Toxoid Vaccine |
1. M/s Biological Evans Ltd Hyderabad |
120 |
|
|
2. Serum Institute, Pune |
96 |
|
|
3. M/s Haffkine Bio-Pharmaceuticals Mumbai (A Govt. of Maharashtra Undertaking) |
71.2 |
|
|
4. Central Resaearch Institute, Kasauli (Unit of MOH) |
30 |
|
|
5. M/s Pasteur Institute of India, Coonoor (Unit of Min of Health & FW) |
30 |
|
|
6. State Vaccine Institute, Patwadangar Nainital |
10 |
|
DT Vaccine |
1. M/s Biological Evans Ltd Hyderabad |
24 |
|
|
2. Central Resaearch Institute, Kasauli (Unit of MOH) |
20 |
|
|
3. M/s Pasteur Institute of India, Coonoor (Unit of Min of Health & FW) |
15 |
|
|
4. M/s Haffkine Bio-Pharmacuticals Mumbai(A Govt. of Maharashtra Undertaking) |
10 |
|
DPT Vaccine |
1. Serum Institute of India, Pune |
97.5 |
|
|
2. M/s Biological Evans Ltd Hyderabad |
80 |
|
|
3. M/s Haffkine Bio-Pharmaceuticals Mumbai (A Govt. of Maharashtra Undertaking) |
44.8 |
|
|
4. M/s Pasteur Institute of India, Coonoor (Unit of Min of Health & FW) |
40 |
|
|
5. Central Research Institute, Kasauli (Unit of MOH) |
25 |
|
Measles Vaccine |
1. Serum Institute of India , Pune |
100 |
|
BCG Vaccine |
1. BCG Vaccine Laboratory, Chennai (Unit of MOH(FW) Tamil Nadu. |
35 |
|
|
|
|
|
Oral Polio Vaccine |
1. M/s Radicura Pharma New Delhi |
540 |
|
|
2. M/s BIBCOL, Bulandshahar |
300 |
|
|
3. M/s Haffkine Bio Pharmaceutical , Mumbai( A Govt. of Maharashtra Undertaking Maharashtra) |
240 |
|
|
4. M/s Biomed , Ghaziabad |
156 |
COLD CHAIN EQUIPMENT
Procurement and replacement of Cold Chain Equipment: Cold Chain is the backbone of the Immunisation programme. About 52,000 Freezer Refrigerators and about 140 Walk-in-Coolers(WICs) & Freezers (WIFs) form a part of the broad network of Cold Chain network in India. These equipments were supplied at various stages of Immunisation Programme during the past with funds from UNICEF and other foreign donor agencies. Their break-down rate (which is worked out as percentage of equipments under repair to total excluding the irrepairable ones) is 1.1%.
NO. OF WALK-IN-COOLERS (WIC) & WALK-IN-FREEZERS (WIF) IN STATES
|
State/Union Territory |
WIC |
WIF |
|
INDIA |
125 |
20 |
|
Andhra Pradesh |
7 |
1 |
|
Arunachal Pradesh |
1 |
0 |
|
Assam |
5 |
1 |
|
Bihar |
9 |
2 |
|
Delhi |
1 |
0 |
|
Goa |
0 |
0 |
|
Gujarat |
6 |
1 |
|
Haryana |
4 |
1 |
|
Himachal Pradesh |
3 |
0 |
|
Jammu & Kashmir |
2 |
0 |
|
Karnataka |
7 |
1 |
|
Kerala |
3 |
0 |
|
Madhya Pradesh |
10 |
2 |
|
Maharashtra |
8 |
2 |
|
Manipur |
1 |
0 |
|
Meghalaya |
2 |
0 |
|
Mizoram |
1 |
0 |
|
Nagaland |
1 |
0 |
|
Orissa |
7 |
1 |
|
Punjab |
4 |
1 |
|
Rajasthan |
7 |
1 |
|
Sikkim |
0 |
0 |
|
Tamil Nadu |
8 |
1 |
|
Tripura |
1 |
0 |
|
Uttar Pradesh |
18 |
4 |
|
West Bengal |
9 |
1 |
|
Andaman & Nicobar Islands |
0 |
0 |
|
Chandigarh |
0 |
0 |
|
Dadra Nagar Haveli |
0 |
0 |
|
Daman & Diu |
0 |
0 |
|
Lakshdeep |
0 |
0 |
|
Pondicherry |
0 |
0 |
In addition to above, there are eight Walk-in-Freezers in Medical Stores Depots of the Ministry of Health & Family Welfare (Govt. of India), two each at Mumbai (Maharashtra), Calcutta (West Bengal), Madras (Tamil Nadu) & Karnal (Haryana).
Statutory testing of vaccines is done by the National Quality Control Laboratory at Kasauli. The vaccines are released only after declared standard by this laboratory. In addition, samples of OPV are picked up from various levels of storage and sent to designated laboratories for potency testing to ensure effectiveness of the Cold Chain system.
The test results for the last nine years indicate steady improvement in the efficacy of the cold chain system in keeping vaccines safe.
DRUGS
Tablets (IFA large and IFA
small )are being supplied under the Reproductive and Child Health
Programme. Vitamin ‘A” solution, ORS
and cotrimoxazole tablets are also
being supplied as a prophylactic against anaemia among pregnant women and
children and for prevention and control of vitamin 'A' deficiency among
children. Cotrimoxazole tablets are being supplied for prevention of Acute
Respiratory Infections (Pneumonia) among children. These five drug items are supplied in the form of kits, named Kit
‘A” to the District Health Officers.
Contents of drug kit ‘A”’ are:
|
Name of the Item |
Quantity |
|
Oral Rehydration Salt (ORS) |
150 packets |
|
Tablet I.F.A(Large) |
15000 |
|
Tablet I.F.A(Small) |
13000 |
|
Vitamin A Solution |
6 bottles of 50 doses each |
|
Tablet Cotrimoxazole (Paediatric) |
1000 |
In the year 1999-2000, 3,03,603
kit ‘A’ were supplied.
In addition to above ,
following drugs in kit ‘B’ are also supplied to the districts. Contents of drug
kit ‘B’ are:
|
Sr. No. |
Name of the item |
Quantity |
|
1 |
Tab Methylergometrine Maleate
(0.125 mg) |
480 tables |
|
2 |
Tablet Paracetamol |
500 tablets |
|
3 |
Inj. Methylergometrine
Maleate (0.2 mg/ml., 1 ml. Ampoule
(for I.M. use) in light resistant Amber colour Ampoules) |
10 Ampoule |
|
4 |
Tab. Mebendazole (100 mg) |
300 tablets |
|
5 |
Tab Dicyclomine Hcl, (10 mg) |
180 tablets |
|
6 |
Chloramphenicol Eye Ointment 1 % W/W in applicaps. Each applicap to contain 250 mg. Of
ointment |
500 Applicaps |
|
7 |
Ointment Povidone Iodine 5 % |
5 Tubes |
|
8 |
Catrimide Powder |
125 gm. |
In the year 1999-2000, 3,03,603 kit ‘B’ were supplied.